1 Advances in Ophthalmic Drug Delivery
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چکیده
5 Various strategies for ocular drug delivery are considered; from basic formulation techniques for 6 improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and 7 penetration enhancers promote drug transport into the eye. The use of drug loaded contact lenses 8 and ocular inserts allows drugs to be better placed where they are needed for more direct 9 delivery. Developments in ocular implants gives a means to overcome the physical barriers that 10 traditionally prevented effective treatment. Implant technologies are under development allowing 11 long term drug delivery from a single procedure, these devices allow posterior chamber diseases 12 to be effectively treated. Future developments could bring artificial corneas to eliminate the need 13 for donor tissue and one-off implantable drug depots lasting the patient’s lifetime. 14 Key Terms 15 Bandage contact lens: Device designed to fit directly onto the front of the eye to offer 16 protection during the healing process, for example, after corneal surgery. 17 Container molecule: Molecular structures with cavities that can accommodate another molecule 18 via guest – host complexation. 19
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تاریخ انتشار 2015